The effects of deliriants (also known as anticholinergics) are often described as mad, panic-inducing, and dysphoric; however, some deliriants can be rather pleasant to some users. They produce their delirium by inhibiting the actions of acetylcholine receptors. The delirium produced by most of these substances can include confusion, stupor, confabulation (the creation of false memories or events), and sometimes euphoria. The striking downside of deliriants remains in their most noteable effects, which include things like finishing a complex task (like getting dressed), only to realize that you haven't even started, being unable to recognize yourself or other people, and having conversations with people that aren't there. Despite this, these effects are sought after by a select few.

Deliriants are easily the most dangerous of hallucinogenic substances. Most cause liver and kidney damage, seizures, and heart complications. They also have a strong ability to bring out schizophrenia-like symptoms even after just weeks of occasional use. Generally, the danger rating for deliriants oftens fall in physical range of 4 to 5 and the mental range of 3 to 5.

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